Hanchuan Peng of Janelia Farm spoke on bioimaging at ISB a couple weeks back. He's doing some very cool work mining microscopy images doing registration - aligning individual cells across images. They've created a 3D atlas of C. elegans which tracks every cell. The still pictures don't don't do it justice. Check out the movies.
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By localizing and registering neural fibers in 2,954 fly brains, Peng's group constructing this wiring diagram of the fly's 100,000 neurons.
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More
- A 3d digital atlas of C. elegans and its application to single-cell analyses, Nature Methods 2009
- BrainAligner: 3d registration atlases of Drosophila brains, Nature Methods 2011
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